Compensatory Evolution of Gene Regulation in Response to Stress by Escherichia coli Lacking RpoS
نویسندگان
چکیده
منابع مشابه
Compensatory Evolution of Gene Regulation in Response to Stress by Escherichia coli Lacking RpoS
The RpoS sigma factor protein of Escherichia coli RNA polymerase is the master transcriptional regulator of physiological responses to a variety of stresses. This stress response comes at the expense of scavenging for scarce resources, causing a trade-off between stress tolerance and nutrient acquisition. This trade-off favors non-functional rpoS alleles in nutrient-poor environments. We used e...
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ژورنال
عنوان ژورنال: PLoS Genetics
سال: 2009
ISSN: 1553-7404
DOI: 10.1371/journal.pgen.1000671